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Empresa Israeli hace crecer hueso nuevo a partir de la grasa del paciente

huesonuevoLa persona promedio tiene dos huesos rotos en su vida, que puede ser causada por todo, desde la artritis, la osteoporosis, los accidentes y efectos secundarios de los medicamentos. Así que no es sorpresa que tratar de curar los huesos rotos es tan antiguo como la propia medicina.

Pero mientras que la reparación de huesos con yesos o injertos óseos autólogos o sintéticos (hueso cosechado de otra parte del cuerpo del paciente) es común, estos pueden ser soluciones inadecuadas.

Ahí es donde israelí BioGroup bonificación empresa de biotecnología entra, con un procedimiento revolucionario que puede crecer hueso nuevo a partir de la grasa de una persona.

La compañía acaba de recibir la aprobación para trasplantar implante de hueso in vitro desarrollada en los seres humanos y la llevará a cabo el primer trasplante de médula en la próxima semana.

«Cortar el hueso de una parte del cuerpo y ponerlo en otra parte es un procedimiento doloroso y costoso,»

Shai Meretzki, CEO de Bono Biogroup, que fue fundada en 2008, cuenta NoCamels. Además, dice, a veces es imposible para injertar la cantidad de hueso necesario. «Así que pensamos: ‘¿por qué no crecemos hueso nuevo mediante el uso de células de pacientes?'»

Esta tecnología pionera crece y se regenera injerto de hueso de alta densidad 3D a partir de las células de grasa. Cultivo injerto de hueso a partir del ADN propio de una persona, Meretzki explica, también «evita cualquier posible rechazo del hueso del cuerpo, ya que es aceptada por el sistema inmune de inmediato.»

Para construir el nuevo hueso, Bono BioGroup recibe muestras de tejido graso del paciente, se extrae a través de la liposucción, junto con una tomografía computarizada del hueso dañado. Posteriormente, el equipo construye un andamio hecho de un material similar a una esponja biodegradable, donde un hueso vivo puede crecer, un procedimiento que toma alrededor de un mes.

Usando tres exploraciones dimensionales del hueso dañado para construir el andamio de tipo gel significa que el equipo puede crear hueso que coincide con la forma exacta needed.Once se crea el hueso, el andamio se descompone naturalmente y lo que queda es el hueso vivo, que se envía a continuación volver al hospital para el paciente para someterse al trasplante.

Crece como cualquier otra parte del cuerpo

«Esta es una solución mejor para el cuerpo que el plástico o metal piezas,» Meretzki afirma. Estos huesos son «huesos vivas activas que pueden crecer; remodelación y cambio como su cuerpo hace. «Incluso con los niños pequeños, cuando se inserta quirúrgicamente el injerto óseo, la nueva adición ajusta y crece como cualquier otra parte del cuerpo.

Situado en Haifa, Israel, instalación Bono de BioGroup contiene un equipo de treinta altamente capacitados biólogos, químicos e ingenieros. Trabajan en laboratorios estériles para crecer, control y análisis de cada hueso individual.

Siguiente paso: cartílago creciente para la curación conjunta

Meretzki previamente fundada Pluristem Therapeutics, una compañía biotecnológica centrada en terapia celular y después de desarrollar la capacidad de crecer una cultura en 3D de las células, se decidió a lanzar Bono Biogroup para ocuparse específicamente de tejido celular y órganos. Este campo, Meretzki recuerda, fue «realmente en la necesidad de un desarrollo para el crecimiento de nuevo tejido activo.»

«En la actualidad,» dice Meretzki NoCamels, «estamos creciendo hueso y el cartílago, pero estamos trabajando en un sistema que combina la propiedad de hueso y cartílago.» Con la esperanza de entrar en el campo de las articulaciones de curación, que es más complejo lo tiene incluye cartílago. «Es un mercado extremadamente desesperada y amplia, con una solución limitada», dice Meretzki.

BioGroup Bono es financiado por inversores privados. La compañía tiene previsto abrir una nueva planta de fabricación en los Estados Unidos en los próximos 18 a 24 meses.

FUENTE: ESTADO DE ISRAEL
FBS\

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